Videographic measurements of optic nerve topography in glaucoma

J. Caprioli, Joseph M Miller

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Topographic measurements of the optic nerve head were made with computerized videographic image analysis (Rodenstock Analyzer) in one eye each of 36 normal controls, 41 glaucoma suspects and 46 glaucoma patients matched for age. Glaucoma suspects had elevated intraocular pressures and normal visual fields in both eyes. Glaucoma patients had typical visual field defects. Disc measurements were corrected for the optical dimensions of individual eyes. One-way analysis of variance revealed statistically significant differences among the diagnostic groups for cup-disc ratio (P = 0.0006), disc rim area (P < 0.0001) and cup volume (P < 0.0001). Mean (±SEM) disc rim area was 1.14 ± 0.04 mm2 for controls, 1.10 ± 0.04 mm2 for glaucoma suspects and 0.87 ± 0.05 mm2 for glaucoma patients. Mean (±SEM) optic nerve cup volume was 0.35 ± 0.02 mm3 for controls, 0.04 ± 0.04 mm3 for glaucoma suspects and 0.60 ± 0.05 mm3 for glaucoma patients. Planimetric measurements of disc rim area were made from manual tracings of stereoscopic disc photographs of the same eyes. There was a statistically significant correlation between the computerized videographic measurements and the manual photographic measurements of disc rim area (r = 0.73, P < 0.0001). The broad range of values for these optic nerve structural parameters in normal eyes and their overlap with values in glaucomatous eyes prevents their use to reliably predict which patients are normal and which have glaucomatous visual field loss. New parameters are required to fully describe the depth information generated with new quantitative techniques.

Original languageEnglish (US)
Pages (from-to)1294-1298
Number of pages5
JournalInvestigative Ophthalmology and Visual Science
Volume29
Issue number8
StatePublished - 1988
Externally publishedYes

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Optic Nerve
Glaucoma
Ocular Hypertension
Visual Fields
Optic Disk
Intraocular Pressure
Analysis of Variance

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Videographic measurements of optic nerve topography in glaucoma. / Caprioli, J.; Miller, Joseph M.

In: Investigative Ophthalmology and Visual Science, Vol. 29, No. 8, 1988, p. 1294-1298.

Research output: Contribution to journalArticle

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