Vitamin D and Liver Disease

R. G. Long, M. R. Wills, Mark R Haussler, Toni A. Mccain

Research output: Contribution to journalLetter

Abstract

To the Editor: In their review of vitamin D metabolism, Haussler and McCain state that osteomalacia is not normally associated with liver disease and infer that vitamin D metabolism may be unimportant in this situation.1 Bone thinning in liver disease has been recognized for many years,2 and histologic evidence of osteomalacia has been reported in numerous series.3 4 5 6 The observed low serum 25-hydroxyvitamin D (25-OHD) concentrations in patients with chronic liver disease appear to be related more to lack of vitamin D substrate than to a failure of 25-hydroxylation, for serum 25-OHD values usually become normal with vitamin D treatment.78 Reed. No extract is available for articles shorter than 400 words.

Original languageEnglish (US)
Pages (from-to)510-511
Number of pages2
JournalNew England Journal of Medicine
Volume298
Issue number9
DOIs
StatePublished - Mar 2 1978

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Vitamin D
Liver Diseases
Osteomalacia
Hydroxylation
Serum
Chronic Disease
Bone and Bones

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Vitamin D and Liver Disease. / Long, R. G.; Wills, M. R.; Haussler, Mark R; Mccain, Toni A.

In: New England Journal of Medicine, Vol. 298, No. 9, 02.03.1978, p. 510-511.

Research output: Contribution to journalLetter

Long, R. G. ; Wills, M. R. ; Haussler, Mark R ; Mccain, Toni A. / Vitamin D and Liver Disease. In: New England Journal of Medicine. 1978 ; Vol. 298, No. 9. pp. 510-511.
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