Vitamin D3 induced alteration of microvillar membrane lipid composition

David B.P. Goodman, Mark R. Haussler, Howard Rasmussen

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

The lipid composition of microvillar membranes prepared from vitamin D3-treated and vitamin D3-deficient chick intestine has been investigated. Vitamin treatment results in an increase in the proportion of phospholipid in this target membrane as well as an alteration in the fatty acid composition of both membrane phospholipids and cholesterol esters. An increase in the weight percentage of several classes of phospholipid long chain polyunsaturated fatty acids results from vitamin treatment. The primary effect of vitamin treatment on cholesterol ester fatty acids appears to be in shorter chain species.

Original languageEnglish (US)
Pages (from-to)80-86
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume46
Issue number1
DOIs
StatePublished - Jan 14 1972

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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