Weight gain and edema on methadone maintenance therapy

Bill Longwell, Thomas Betz, Herschella Horton, Charles L. Witte, Marlys H Witte

Research output: Contribution to journalArticle

Abstract

Methadone HCl is currently legally dispensed to approximately 80,000 heroin addicts in the United States. It is widely heralded as being virtually free from other than narcotic side effects. This report describes in detail three patients with massive fluid gain in a population of 420 addicts treated at the Hope Center methadone program in Tucson, Arizona. In no patient was there a prior history of edema, and an intensive search failed to reveal a cause for the swelling. Weight gain uniformly began 3 to 6 months after initiation of methadone or a sharp increase in the dosage, and in all three patients during periods when they sharply reduced or discontinued methadone, edema was resolved associated with a concomitant loss of weight.

Original languageEnglish (US)
Pages (from-to)329-335
Number of pages7
JournalSubstance Use and Misuse
Volume14
Issue number3
DOIs
StatePublished - 1979

Fingerprint

Methadone
addiction
Weight Gain
Edema
drug
cause
Narcotics
Heroin
Therapeutics
Weight Loss
Population

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Public Health, Environmental and Occupational Health
  • Health(social science)
  • Medicine (miscellaneous)

Cite this

Weight gain and edema on methadone maintenance therapy. / Longwell, Bill; Betz, Thomas; Horton, Herschella; Witte, Charles L.; Witte, Marlys H.

In: Substance Use and Misuse, Vol. 14, No. 3, 1979, p. 329-335.

Research output: Contribution to journalArticle

Longwell, Bill ; Betz, Thomas ; Horton, Herschella ; Witte, Charles L. ; Witte, Marlys H. / Weight gain and edema on methadone maintenance therapy. In: Substance Use and Misuse. 1979 ; Vol. 14, No. 3. pp. 329-335.
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