When the fire won't go out: Pomegranate juice, sildenafil, CYP3A4

Thomas P. Pontinen, Randal O. Dull

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This case discusses the pharmacokinetic interaction between pomegranate juice and sildenafil, resulting in priapism. Sildenafil is a cytochrome P450 3A4 substrate and pomegranate juice is a 3A4 inhibitor.

Original languageEnglish (US)
Title of host publicationA Case Approach to Perioperative Drug-Drug Interactions
PublisherSpringer New York
Pages859-861
Number of pages3
ISBN (Electronic)9781461474951
ISBN (Print)9781461474944
DOIs
StatePublished - Sep 15 2015
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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