Wikstromol, antitumor lignan from Wikstroemia foetida var. oahuensis gray and Wikstroemia uva‐ursi gray (thymelaeaceae)

Sterling J. Torrance, Joseph J. Hoffmann, Jack R. Cole

Research output: Contribution to journalComment/debate

59 Scopus citations

Abstract

The ethanol extracts of Wikstroemia foetida var. oahuensis and Wikstroemia uva‐ursi showed antitumor activity against the P‐388 lymphocytic leukemia (3PS) test system. One PS‐active constituent of both plants was the lignan wikstromol. Several inactive compounds were identified as daphnoretin, pinoresinol, and syringaresinol.

Original languageEnglish (US)
Pages (from-to)664-665
Number of pages2
JournalJournal of pharmaceutical sciences
Volume68
Issue number5
DOIs
StatePublished - May 1979

Keywords

  • Antineoplastic agents—wikstromol, isolated from plant material
  • Wikstromol—isolation from plant material, antineoplastic activity

ASJC Scopus subject areas

  • Pharmaceutical Science

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