Wound inflammatory index: A "proof of concept" study to assess wound healing trajectory

Manish Bharara, Jeffrey Schoess, Aksone Nouvong, David G Armstrong

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Diabetes around the globe results in one major limb amputation every 30 seconds, over 2500 limbs lost per day. The underlying pathophysiology sometimes leads to a chronic inflammatory stage, which may prevent appropriate healing, and therefore, the need for a clear strategy for assessing and classifying wounds and wound healing cannot be overstated. Temperature is a surrogate marker for inflammation. Quantitative thermography using a numerical index provides a useful way to assess wound healing. Advances in technology have afforded the availability of low-cost, high-resolution thermal imaging systems, which can be used to quantify sensitive changes on the skin surface and may be particularly useful to develop monitoring strategies for wounds. This article provides a standardized technique for calculating a thermal index (TI) supported with a case report from assessment of a diabetic foot ulcer. In this single case study, the TI/wound inflammatory index indicates a shift from negative to positive (p < .05) before it reaches zero.

Original languageEnglish (US)
Pages (from-to)773-779
Number of pages7
JournalJournal of diabetes science and technology
Volume4
Issue number4
Publication statusPublished - Jul 2010

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Keywords

  • Diabetic foot ulcers
  • Thermal index
  • Thermography
  • Thermometry
  • Wound healing

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine
  • Bioengineering
  • Biomedical Engineering

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